pylori) infection and non-steroidal anti-inflammatory drugs (NSAIDs)/aspirin (ASA) use are the major culprits for causing gastroduodenal mucosal injuries. According to previous studies, peptic ulcer disease (PUD) occurred in 2.4–3.5% of the Western populace, 12–15% of Asian inhabitants, and 24–28% of sub-Saharan African dwellers. Dyspepsia has an impact on the quality of life of patients and the expenses to the health care service. Globally, dyspepsia occurs in 10–20% of adults, and accounts for 3% of medical office visits. It can manifest as postprandial fullness, early satiety, or epigastric burning or pain. It is described as predominant epigastric pain lasting for at least one month. pylori infection and cautious use of non-steroidal anti-inflammatory drugs/aspirin.ĭyspepsia is a common complaint in upper gastrointestinal disorders. Medical treatment of peptic ulcer disease should target treatment of H. Peptic ulcer disease was diagnosed in 35% (95% CI 31.4–39.2) of patients with dyspepsia. Forty nine percent (95% CI 42.4–56.2) of dyspeptic patients had active H. The mean (+ SD) age of patients was 42 ± 16.4 years. P value < 0.05 was used to declare significant association.Ī total of 218 dyspeptic patients who underwent upper gastrointestinal endoscopic evaluations were included in the study. Explanatory variables associated with peptic ulcer disease were analyzed by applying logistic regression model. The Data were entered into EPI Info version 4.6.0.2, and then exported to SPSS version 20 for analysis. pylori Antigen 25 T Card Test (Anamol Lab., Pvt. pylori infection was made using the fecal H. Olympus flexible fiber-optic endoscope (Olympus, GIF-E 600, Olympus Corp., Hamburg, Germany) was used to confirm the presence of peptic ulcer disease. A pre-designed semi-structured questionnaire was used to extract clinical information. A convenience sampling method was used to recruit 218 study subjects. MethodsĪn institutional-based cross sectional study was conducted at the University of Gondar hospital, Northwest Ethiopia. This study aimed to determine magnitude and associated factors of peptic ulcer disease among dyspeptic patients in Northwest Ethiopia. pylori infection rate among patients with peptic ulcer disease in Ethiopia. pylori) infection and non-steroidal anti-inflammatory drugs/aspirin use are the widely known risk factors for peptic ulcer disease. Globally, peptic ulcer disease occurs in 3.5–32% of patients with dyspepsia. Dyspepsia is a common complaint in upper gastrointestinal disorders.
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